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National Emergency Preparedness Node Network

Stockpile the inputs, not the pills.

Validated digital recipes, held under one quality system and released in an emergency to qualified CraftMake™ sites that print the doses needed, where and when they are needed.

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503A pharmaciesHospital pharmaciesRegional nodesFederal sitesPharmaTher control siteQuality system · recipe libraryLocations illustrative

The gap

Stockpiles hold fixed, mostly adult strengths.

Emergency stockpiles hold finished medicines in fixed, mostly adult strengths, and the U.S. is building a reserve of raw drug ingredients that must be made into doses when needed. Children, infants and patients with kidney disease often need strengths the stockpile doesn't hold.

~26Critical drugs prioritized for the U.S. Strategic Active Pharmaceutical Ingredients Reserve
10,000+Potential preparedness nodes in North America (management estimate)

How the network works

Commercial work in peacetime. Countermeasures in an emergency.

1ValidateDigital recipes for priority medicines are validated and held under one quality system.
2QualifyPharmacies, hospitals, CDMOs and government facilities with CraftMake™ systems are qualified as nodes.
3Stay readyIn peacetime, the printers do commercial work, and governments pay readiness fees to keep the network ready.
4Print on demandIn an emergency, recipes are released to the nodes, which print the doses needed, including for children.

The network is designed to complement national stockpiles, not replace them.

Why now

A reserve of ingredients needs a way to make doses.

PharmaTher is evaluating the approximately 26 critical drugs prioritized for the U.S. Strategic Active Pharmaceutical Ingredients Reserve, which the U.S. Administration for Strategic Preparedness and Response (ASPR) manages under a 2025 executive order. The goal is to determine which can be developed as validated digital recipes, so that stockpiled ingredients could be printed into ready-to-use doses, including for children, at qualified sites during an emergency.

Next 12 months

Demonstration and readiness contracts

PharmaTher plans to complete a demonstration and pursue readiness contracts with U.S. and Canadian agencies, including ASPR and Defence Research and Development Canada (DRDC).

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Governments and institutions

ASPR, BARDA, DRDC, DoD/DHA, provinces, hospitals and CDMOs: talk to us about a demonstration.

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Become a node

Every CraftMake™ placement can become a node. Start on M3DICINES.

Become a National Emergency Partner ↗

Node locations are illustrative. Nodes require site qualification, and readiness contracts are prospective. There is no finalized FDA framework for distributed manufacturing, and government funding and procurement are uncertain. The number of potential sites is a management estimate. Plans and timelines are forward-looking.